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27-Nov-2016 19:47

Some children may display hyperactivity or self-abusive behaviors.

While children with cri du chat syndrome are born hypotonic (low muscle tone), they tend to become hypertonic (high muscle tone) as they grow older.

Improper alignment of the upper and lower teeth (malocclusion) may also occur.

Additional facial features include an abnormally small distance from the upper lip to the nose (short philtrum), incomplete closure of the roof of the mouth (cleft palate), an abnormal groove or gap in the upper lip (cleft lip), and abnormal fullness of the lower lip.

In French, Cri du chat translates into “cry of the cat”.

The symptoms of cri du chat syndrome vary from case to case.

About half of children with cri du chat syndrome were able to dress themselves by age 5 years.

Moderate to severe intellectual disability is present in most cases.

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Distinctive facial features may include an abnormally round or plump (moon) face, a broad nasal bridge, widely spaced eyes (hypertelorism), crossed eyes (strabismus), downwardly slanting eyelid folds (palpebral fissures), vertical skin folds that may cover the eyes’ inner corners (epicanthal folds), low-set ears, and an abnormally small jaw (micrognathia).

In addition, the fleshy mass (uvula) that hangs in the back of the throat may be spilt (bifid uvula).

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